650 research outputs found

    NASA TileWorld manual (system version 2.2)

    Get PDF
    The commands are documented of the NASA TileWorld simulator, as well as providing information about how to run it and extend it. The simulator, implemented in Common Lisp with Common Windows, encodes a particular range in a spectrum of domains, for controllable research experiments. TileWorld consists of a two dimensional grid of cells, a set of polygonal tiles, and a single agent which can grasp and move tiles. In addition to agent executable actions, there is an external event over which the agent has not control; this event correspond to a 'gust of wind'

    Integrating genealogical and dynamical modelling to infer escape and reversion rates in HIV epitopes

    Get PDF
    The rates of escape and reversion in response to selection pressure arising from the host immune system, notably the cytotoxic T-lymphocyte (CTL) response, are key factors determining the evolution of HIV. Existing methods for estimating these parameters from cross-sectional population data using ordinary differential equations (ODE) ignore information about the genealogy of sampled HIV sequences, which has the potential to cause systematic bias and over-estimate certainty. Here, we describe an integrated approach, validated through extensive simulations, which combines genealogical inference and epidemiological modelling, to estimate rates of CTL escape and reversion in HIV epitopes. We show that there is substantial uncertainty about rates of viral escape and reversion from cross-sectional data, which arises from the inherent stochasticity in the evolutionary process. By application to empirical data, we find that point estimates of rates from a previously published ODE model and the integrated approach presented here are often similar, but can also differ several-fold depending on the structure of the genealogy. The model-based approach we apply provides a framework for the statistical analysis of escape and reversion in population data and highlights the need for longitudinal and denser cross-sectional sampling to enable accurate estimate of these key parameters

    An analysis of commitment strategies in planning: The details

    Get PDF
    We compare the utility of different commitment strategies in planning. Under a 'least commitment strategy', plans are represented as partial orders and operators are ordered only when interactions are detected. We investigate claims of the inherent advantages of planning with partial orders, as compared to planning with total orders. By focusing our analysis on the issue of operator ordering commitment, we are able to carry out a rigorous comparative analysis of two planners. We show that partial-order planning can be more efficient than total-order planning, but we also show that this is not necessarily so

    Ground Systems Development Environment (GSDE) interface requirements and prototyping plan

    Get PDF
    This report describes the data collection and requirements analysis effort of the Ground System Development Environment (GSDE) Interface Requirements study. It identifies potential problems in the interfaces among applications and processors in the heterogeneous systems that comprises the GSDE. It describes possible strategies for addressing those problems. It also identifies areas for further research and prototyping to demonstrate the capabilities and feasibility of those strategies and defines a plan for building the necessary software prototypes

    The APT/ERE planning and scheduling manifesto

    Get PDF
    The Entropy Reduction Engine, ERE project, is focusing on the construction of integrated planning and scheduling systems. Specifically, the project is studying the problem of integrating planning and scheduling in the context of the closed loop plan use. The results of this research are particularly relevant when there is some element of dynamism in the environment, and thus some chance that a previously formed plan will fail. After a preliminary study of the APT management and control problem, it was felt that it presents an excellent opportunity to show some of the ERE Project's technical results. Of course, the alignment between technology and problem is not perfect, so planning and scheduling for APTs presents some new and difficult challenges as well

    Planning, scheduling, and control for automatic telescopes

    Get PDF
    This paper presents an argument for the appropriateness of Entropy Reduction Engine (ERE) technology to the planning, scheduling, and control components of Automatic Photoelectric Telescope (APT) management. The paper is organized as follows. In the next section, we give a brief summary of the planning and scheduling requirements for APTs. Following this, in section 3, we give an ERE project precis, couched primarily in terms of project objectives. Section 4 gives a sketch of the match-up between problem and technology, and section 5 outlines where we want to go with this work

    Applying artificial intelligence to the control of space telescopes (extended abstract)

    Get PDF
    The field of astronomy has recently benefited from the availability of space telescopes. The Hubble Space Telescope (HST), for instance, despite its problems, provides a unique and valuable view of the universe. However, unlike HST, a telescope need not be in low Earth orbit to escape our thickening atmosphere: it is currently technologically feasible to put a telescope on the moon, and there are excellent reasons for doing this. Either in low Earth orbit or on the moon, a space telescope represents an expensive and sought-after resource. Thus, the planning, scheduling, and control of these telescopes is an important problem that must be seriously studied

    Ground Systems Development Environment (GSDE) interface requirements analysis

    Get PDF
    A set of procedural and functional requirements are presented for the interface between software development environments and software integration and test systems used for space station ground systems software. The requirements focus on the need for centralized configuration management of software as it is transitioned from development to formal, target based testing. This concludes the GSDE Interface Requirements study. A summary is presented of findings concerning the interface itself, possible interface and prototyping directions for further study, and results of the investigation of the Cronus distributed applications environment
    • …
    corecore